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KMID : 0356620060210060548
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Journal of Korean Society of Endocrinology
2006 Volume.21 No. 6 p.548 ~ p.551
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A Case of Methimazole-induced Pancytopenia: Successful Treatment with Recombinant Human Granulocyte Colony-stimulating Factor
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이주형
이지현/성상훈/배성화/김상경/오훈규
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Abstract
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Methimazole has remained the cornerstone for the treatment of hyperthyroidism since 1940's and it is a well-tolerated antithyroid drug. Pancytopenia is one of the major side effects of methimazole, but its occurrence is very rare. There have been some case reports about methimazole-induced pancytopenia that was treated with recombinant human granulocyte colony-stimulating factor (G-CSF), but its usefulness is still controversial. We present here a case of a 50-year-old female who had been treated with methimazole for hyperthyroidism and she subsequently presented pancytopenia. G-CSF was given for 10 days and she successfully recovered from the pancytopenia.
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KEYWORD
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Hyperthyroidism, Methimazole, Pancytopenia, Recombinant human granulocyte colony-stimulating factor
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